B-(6-Chloro-2-pyridinyl)boronic acid

B-(6-Chloro-2-pyridinyl)boronic acid - Names and Identifiers

Name	(6-chloropyridin-2-yl)boronic acid
Synonyms	2-Borono-6-chloropyridine 6-chloropyridin-2-yl-2-boronic 6-Chloropyridine-2-boronicacid 6-Chloropyridine-2-boronic acid 6-Chloro-2-pyridineboronic acid (6-Chloro-2-pyridyl)boronic acid (6-CHLORO-2-PYRIDINYL)BORONIC ACID (6-Chloro-2-pyridinyl)boronic acid (6-chloropyridin-2-yl)boronic acid B-(6-Chloro-2-pyridinyl)boronic acid B-(6-CHLORO-2-PYRIDINYL)BORONIC ACID boronic acid, B-(6-chloro-2-pyridinyl)- 2-chloro-6-(dihydroxy-l3-bromanyl)pyridine
CAS	652148-90-8
InChI	InChI=1/C5H5BClNO2/c7-5-3-1-2-4(8-5)6(9)10/h1-3,9-10H

B-(6-Chloro-2-pyridinyl)boronic acid - Physico-chemical Properties

Molecular Formula	C5H5BClNO2
Molar Mass	157.36
Density	1.41
Boling Point	355℃
Flash Point	169℃
Vapor Presure	1.17E-05mmHg at 25°C
pKa	6.82±0.53(Predicted)
Storage Condition	Inert atmosphere,Store in freezer, under -20°C
Refractive Index	1.559

B-(6-Chloro-2-pyridinyl)boronic acid - Introduction

(6-chloropyridin-2-yl)boronic acid is an organic compound whose chemical formula is C5H4BClNO2. The following is a description of the properties, uses, preparation and safety information of the compound:

Nature:
-Appearance: Colorless to light yellow solid;
-Solubility: Soluble in some organic solvents, such as dimethyl sulfoxide and ethanol;
-Melting point: about 180-185°C.

Use:
(6-choropyridin-2-yl) boronic acid is an important organic synthesis intermediate, commonly used in organic chemical synthesis reactions. It can be used as a substitute reagent for aromatic compounds and is used in the synthesis of various organic compounds, such as drug molecules, pesticides and coating materials.

Preparation Method:
(6-chloropyrin-2-yl) The preparation method of boronic acid is usually to use boric acid and 2-chloro-6-pyridine borate (2-chloro-6-boronopyridine) as raw materials, and obtain the product through appropriate reaction conditions. The specific preparation method can be adjusted according to specific requirements and reaction conditions.

Safety Information:
- (6-choropyridin-2-yl) boronic acid is generally considered to be less harmful to human body and environment, it is still necessary to pay attention to the correct operation and storage methods of chemicals;
-When using the compound, it is recommended to wear appropriate protective equipment, such as gloves, glasses, etc., to prevent skin contact and aspiration;
-The compound may be irritating to the eyes and respiratory system. If it comes into contact with skin or eyes, rinse with plenty of water and seek medical help;
-Keep away from fire and oxidant during use and storage to avoid fire or explosion.

Last Update：2024-04-09 15:17:59